翻訳と辞書 Words near each other ・ Clothing in Africa ・ Clothing in ancient Egypt ・ Clothing in ancient Greece ・ Clothing in ancient Rome ・ Clothing in India ・ Clothing in Mauritius ・ Clothing in the ancient world ・ Clothing in the Ragtime Era ・ Clothing insulation ・ Clothing label ・ Clothing laws by country ・ Clothing material ・ Clothing of Balochistan, Pakistan ・ Clostridium difficile (bacteria) ・ Clostridium difficile colitis ・ Clostridium difficile toxin A ・ Clostridium difficile toxin B ・ Clostridium enterotoxin ・ Clostridium estertheticum ・ Clostridium fallax ・ Clostridium formicaceticum ・ Clostridium histolyticum ・ Clostridium innocuum ・ Clostridium kluyveri ・ Clostridium lavalense ・ Clostridium leptum ・ Clostridium ljungdahlii ・ Clostridium novyi ・ Clostridium paradoxum ・ Clostridium paraputrificum Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Clostridium difficile toxin A ： ウィキペディア英語版 Clostridium difficile toxin A Clostridium difficile toxin A (TcdA) is a toxin generated by ''Clostridium difficile''. It is similar to ''Clostridium difficile'' Toxin B. The toxins are the main virulence factors produced by the gram positive, anaerobic, ''Clostridium difficile'' bacteria. The toxins function by damaging the intestinal mucosa and cause the symptoms of ''C. difficile'' infection, including pseudomembranous colitis. TcdA is one of the largest bacterial toxins known. With a molecular mass of 308kDa, it is usually described as a potent enterotoxin, but it also has some activity as a cytotoxin. The toxin acts by modifying host cell GTPase proteins by glucosylation, leading to changes in cellular activities. Risk factors for ''C. difficile'' infection include antibiotic treatment, which can disrupt normal intestinal microbiota and lead to colonization of ''C. difficile'' bacteria. == ''tcdA'' gene == The gene contains an open reading frame (ORF) of 8,133 nucleotides, coding for 2,710 amino acids. TcdA and TcdB share 63% homology in their amino acid sequences. These genes are expressed during late log phase and stationary phase in response to environmental factors. Environmental stresses such as antibiotics and catabolite repression can influence toxin expression. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Clostridium difficile toxin A」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.